What is varicella-zoster titer?

What is varicella-zoster titer?

This test looks for antibodies in your blood that your body makes against the varicella-zoster virus. The varicella-zoster virus is very contagious. It can cause two health problems: chickenpox and shingles. When you become infected with the virus for the first time, it causes chickenpox.

What is varicella IgG titer?

Varicella Titer (or VZV titer or varicella antibody titer test) is another type of testing process that is used for checking the concentration of IgM and IgG antibodies in the blood. In other words, it is a blood test for chickenpox antibodies.

What is varicella interpretation?

Interpretation. A positive IgM result indicates a recent infection with varicella-zoster virus (VZV). A negative result does not rule out the diagnosis of VZV infection. The specimen may have been drawn before the appearance of detectable antibodies.

What tube is used for varicella titer?

red top tube or other plain sterile tube without anticoagulant and allowed to clot at room temperature. serum to a plain polypropylene tube and refrigerate. If testing is delayed longer than 7 days, serum should be frozen at -20ºC or colder.

What is a positive varicella zoster antibody?

A positive VZV IgG result indicates the presence of antibodies to varicella zoster virus. The test cannot distinguish between past infection and current infection though, so a positive result could indicate active infection and not immunity.

Should varicella titer be negative or positive?

If exposure to varicella-zoster virus is suspected, despite a negative finding, a second sample should be collected and tested no less than one or two weeks later. Positive results indicate the presence of detectable VZV IgG antibodies.

What lab tests varicella titer?

IgG ELISA. A single serologic IgG test can be used to determine if a person has antibodies to VZV from past varicella disease or who may be candidates for varicella-zoster immune globulin (VZIG).

Do I need a varicella titer?

A: If you have a history of having had chicken pox, you will still need to obtain a varicella titer showing immunity.

What is a positive varicella titer range?

165.0 IV or greater: Positive – IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. 0.90 ISR or less: Negative – No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal – Repeat testing in 10-14 days may be helpful.

What is a high titer level?

The antibody titer score is generated by the number of times the scientist can dilute a patient’s serum and still be able to detect the presence of antibodies. Titers of 1:80 and 1:160 were categorized as low titers; 1:320 moderate; and 1:960 or ≥ 1:2880 were high.