Can you have a baby with MTHFR?
While women can get pregnant with an MTHFR gene mutation, they may have an increased risk of complications during pregnancy, including preeclampsia, congenital birth defects, and polycystic ovarian disease (PCOD).
What does methylenetetrahydrofolate reductase do?
The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. This enzyme plays a role in processing amino acids, the building blocks of proteins. Methylenetetrahydrofolate reductase is important for a chemical reaction involving the vitamin folate (also called vitamin B9).
Can methylenetetrahydrofolate reductase deficiency be cured?
MTHFR mutations do not require medical treatment. That said, making dietary and lifestyle changes can often help offset any resulting nutritional deficiencies. For example, people with high homocysteine levels due to folate or vitamin B12 deficiencies can take folic acid or vitamin B12, respectively.
What happens if you have MTHFR and take folic acid?
Folic acid: Supplementation with folic acid may compensate for the reduced MTHFR enzyme activity, leading to normal levels of the active L-methylfolate, which may have an impact on depression response. Studies investigating the effect of folic acid supplementation on depression response have produced mixed results.
How is MTHFR treated in pregnancy?
Positive mutated MTHFR gene treatment options
- Lovenox or heparin injections. These injections can help prevent blood clots from forming between the developing placenta and the uterine wall.
- Daily aspirin (81 milligrams).
- Prenatal vitamin with L-methylfolate.
What is Mthfr deficiency methylenetetrahydrofolate?
Methylenetetrahydrofolate Reductase (MTHFR) Deficiency is the most common genetic cause of elevated levels of homocysteine in the plasma (hyperhomocysteinemia). The MTHFR enzyme plays an important role in processing amino acids, specifically, the conversion of homocysteine to methionine.
Does MTHFR cause miscarriages?
There’s no scientific evidence that MTHFR gene mutations cause recurrent pregnancy loss, but women who’ve had multiple pregnancy losses often test positive for the MTHFR gene mutation. Pregnant women who have a positive MTHFR mutated gene may go on to have complications during pregnancy.
Should I take baby aspirin if I have MTHFR?
Avoid Environmental and Food Toxins – Those with the defect have a harder time eliminating toxins, so focus on not putting them in your body in the first place. Take Baby Aspirin – If trying to conceive or pregnant your doctor may advise you to take a baby aspirin daily to help minimize the chances of a blood clot.
How does MTHFR affect pregnancy?
Some health conditions and disorders can result without enough folate, or with a malfunctioning MTHFR gene. During pregnancy, women who test positive for a mutated MTHFR gene may have a higher risk for miscarriages, preeclampsia, or a baby born with birth defects, such as spina bifida.
Is folic acid bad for MTHFR?
You might have read or heard that folic acid is not safe if you have one or two copies of the MTHFR C677T variant. This is not true. Even if you have one or two copies of the MTHFR C677T variant, your body can safely and effectively process the different types of folate, including folic acid.
Are there any prenatal vitamins for women with MTHFR?
Some women have considered taking vitamins during pregnancy. This might help reduce the risk of birth defects. There are several vitamins to choose from. We already covered the importance of folate for pregnant women with an MTHFR defect. Here are a few other prenatal vitamins some women take in supplement form.
Are there any genetic tests for MTHFR deficiency?
The NIH Genetic Testing Registry, GTR, displays genetic tests that are currently available for the MTHFR gene and for homocysteinemia due to MTHFR deficiency. Biochemical genetic tests may also be used, which assess the level of activity of the MTHFR enzyme or the level of analyte in the blood.
Can a person with MTHFR C677T process folate?
People with MTHFR C677T variants can process all types of folate, including folic acid. Folate is a general term for many different types of vitamin B9.
Which is better for neural tube defects folate or MTHFR?
Even if you have one or two copies of the MTHFR C677T variant, your body can safely and effectively process the different types of folate, including folic acid. Folic acid is the only type of folate shown to help prevent neural tube defects. 1, 3, 4, 6, 10