What are the effects of the Marburg virus?
Nausea, vomiting, chest pain, a sore throat, abdominal pain, and diarrhea may appear. Symptoms become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhaging, and multi-organ dysfunction.
How does the Marburg virus enter the human body?
The virus spreads through direct contact (such as through broken skin or mucous membranes in the eyes, nose, or mouth) with: Blood or body fluids* (urine, saliva, sweat, feces, vomit, breast milk, amniotic fluid, and semen) of a person who is sick with or died from Marburg virus disease, or.
What disease does Marburg virus cause?
Marburg virus disease. Marburg hemorrhagic fever is a severe and highly fatal disease caused by a virus from the same family as the one that causes Ebola hemorrhagic fever. Both diseases are rare, but can cause dramatic outbreaks with high fatality. There is currently no specific treatment or vaccine.
How does the Marburg virus affect the immune system?
One hypothesis for the induction of severe pathogenesis in Marburg-infected individuals is that the hyperactivation of immune cells results in the release of massive amounts of cytokines. This in turn results in the induction of a hemorrhagic, septic, shock-like response.
What is the fatality rate of Marburg virus?
The virus causes severe viral haemorrhagic fever in humans. The average MVD case fatality rate is around 50%. Case fatality rates have varied from 24% to 88% in past outbreaks depending on virus strain and case management.
What is the difference between Marburg and Ebola?
Marburg and Ebola viruses are filamentous filoviruses that are distinct from each other but that cause clinically similar diseases characterized by hemorrhagic fevers and capillary leakage. Ebola virus infection is slightly more virulent than Marburg virus infection.
Is Marburg virus painful?
Symptoms of Marburg virus disease Illness caused by Marburg virus begins abruptly, with high fever, severe headache and severe malaise. Muscle aches and pains are a common feature. Severe watery diarrhoea, abdominal pain and cramping, nausea and vomiting can begin on the third day.
What kind of disease does Marburg virus cause?
Key facts 1 Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever, is a severe, often fatal illness in humans. 2 Rousettus aegyptiacus, fruit bats of the Pteropodidae family, are considered to be natural hosts of Marburg virus. 3 The Marburg virus causes severe viral haemorrhagic fever in humans.
How is Marburg transmitted from person to person?
Transmission of the virus via contaminated injection equipment or needle-stick injuries is associated with more severe disease. Close contact with the body or body fluids of people who have died of Marburg during preparation for burial is a recognised source of infection.
How long does it take to show symptoms of Marburg virus?
In many cases, symptoms appear about a week (five to 10 days) after someone is infected with the virus, 5 but they can come on anywhere from two days to three weeks. Marburg virus disease is often fatal.
What to do if you have Marburg virus?
Healthcare workers caring for patients with suspected or confirmed Marburg virus should apply extra infection control measures to prevent contact with the patient’s blood and body fluids and contaminated surfaces or materials such as clothing and bedding.